Tuberculosis of the Glans Penis Presenting as Glans Gangrene

Tuberculosis of the glans penis is rare. The clinical features of tuberculosis of the glans penis include the appearance of a superficial ulcer of the glans. We recently experienced a case of tuberculosis of the glans penis presenting as an ulcer, which progressed to glans necrosis. A 46-year-old man presented at our institution with painful ulcerative penile lesions. Initial pathological findings of the ulcers showed non-granulomatous inflammatory changes. He was treated with antibiotics and anti-inflammatory drugs for 6 months, and during that time, his glans ulcers progressed to glans gangrene. A partial glansectomy showed multiple epithelioid granulomas with central caseous necrosis, which was compatible with the findings of tuberculosis. The patient received anti-tuberculosis chemotherapy. The current case is reported to alert physicians to consider the possibility of tuberculosis when evaluating unusual penile glans lesions.